Mettler-Toledo tackles Indian pharmaceutical packaging

The Mettler-Toledo StarWeigh checkweigher for high precision weighing of liquid pharmaceuticals. Photo Mettler Toledo

Pharmaceutical manufacturers need to validate and reproduce certain events with 100% accuracy because no exceptions are tolerated in this key healthcare industry. Pharmaceutical companies implement several types of quality controls, whether X-rays, visual detection systems or checkweighing, to ensure that each step of their production chain produces guaranteed drugs. 100% free of manufacturing defects. Mettler-Toledo, with its wide range of inspection systems and presence in India, provides the pharmaceutical manufacturing and packaging industries with reliable solutions.

South Asia Packaging Editor-in-Chief Naresh Khanna and Correspondent Priyanka Tanwar recently interacted online with Miriam Krechlok, Head of Pharmaceutical Marketing, and Wolf Pries, Head of Sales, Mettler-Toledo about the company’s inspection solutions for pharmaceutical products and their potential appeal to Indian pharmaceutical manufacturers and co-owners of packaging facilities. Trends in liquid drug packaging and inspection and compatibility with inkjet marking engines were also discussed.

Mettler-Toledo product inspection devices can be used inline in highly automated packaging lines as well as offline when the manual packaging process is used. Pries mentions: “When we talk about vaccine production, for example, these lines process 600 vials per minute and that is, of course, impossible to inspect offline with a manual process. In 90% or 95% of the cases, the inspection machines are online and doing their job by themselves.

According to Pries, offline inspection is primarily used when there may be a product recall, and inspection personnel manually re-inspect the product that has been recalled and identify the batch that caused the recall. It doesn’t have much application in the pharmaceutical industry, he says.

Foreign body contamination inspection

Kreclok says that when it comes to the mixing area of ​​powdered products, Mettler-Toledo offers the gravity drop option to detect foreign contamination in powders. In the capsules, there is the critical control point of contamination with regard to the capsule machine, and for this, the Tableaux product is intended for the inspection of the capsules.

Miriam Krechlok, pharmaceutical marketing manager, Mettler-Toledo. Photo Mettler-Toledo

“After the blister machine, for example, we can use an X-ray machine. When the blisters pass the blister packing station, we offer security control solutions where we have different products for aggregation and fulfillment” , she continues. Pries adds that individual tablets are inspected for foreign body contamination, including metal contamination in their inspection solutions.

Checking for packaging defects

Mettler-Toledo’s spot inspection devices are the main reason for its strong presence in the pharmaceutical market. Survey inspection devices offer visual inspection by cameras and also allow for OEM integration. TM solutions also verify visual inspections, for example by detecting a missing tablet in a blister or a broken tablet in a blister. Thus, a wide range of inspections can be covered by vision or camera inspection.

Indian pharmaceutical companies and co-packing facilities

India is a strategic market not only directly linked to pharmaceutical companies but also for a large number of co-packers or contract packers. Mettler-Toledo in India holds a significant market share in the pharmaceutical packaging operations segment of the country. “The great flexibility of Mettler-Toledo products and easy line integration could be a huge selling point on our side for the co-packer industry in the country,” Kreclok points out.

Pries adds, “Indian co-packers and local pharmaceutical companies are also working globally and exporting their drugs to Europe, North America and other territories. They should know that we are not only experts in product inspection, but also experts in international regulations and compliance. All of our products comply with USFDA or European authority standards or standards in India and other Asian countries.

Compatibility with inkjet marking systems

Pries explains, “We carry our visual contamination and checkweigh products. In many cases where we do not offer our own products, we partner with our customers’ preferred vendor and integrate third-party equipment into our products as necessary. Domino, Videojet and Markem-Imaje are some of the coding and marking companies we work with.

“If you’re in the pharmaceutical industry, Domino is the global market leader. We also did laser marking with the Aczet laser. We work with these third party partners and ensure that the different devices communicate with each other so that the printer requests data from us and we ensure that the protocols are in line and the printer will understand our message. This is also valuable when talking about integration with the PLC (programmable logic controller). We have a close relationship with Siemens or with Allen Bradley and consultancy services are a very important part of our business. »

Mettler-Toledo Addresses Liquid Pharmaceutical Trends

The Covid-19 pandemic and subsequent vaccination campaigns have led to high demand for pharmaceutical drugs in the field of liquids in India and across the globe. This emerging trend has inspired Mettler-Toledo to develop new products for the liquid pharmaceuticals segment, namely the StarWeigh checkweigher for high-precision weighing of liquid pharmaceuticals and the Mettler-Toledo T60 Integrated 360 series, offering capabilities advances in track and trace to the pharmaceutical market for round objects such as bottles and vials used in liquid drug packaging.

The growing demand for liquid formulations has also given the company greater demand for its product inspection solutions in the country. According to Kreclok, “We see that the trend with liquid pharmaceuticals is growing and we will develop new products, according to the new trends.”

NOTE — This article is taken from the February issue of South Asia Packaging which will be made available to readers on February 4, 2022.

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