Augmented formulation of nanomaterials of disinfectants and antiseptics in the control of SARS CoV-2

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Food Environ Virol. 2022 Mar 9. doi: 10.1007/s12560-022-09517-0. Online ahead of print.

ABSTRACT

The global COVID-19 pandemic has drawn particular attention towards innovative strategies to overcome viral spread. Nanotechnology will change our lives in many forms, as its uses range from electronics to pharmaceutical procedures. The use of nanoparticles offers the possibility of promoting new antiviral treatments with a low possibility of increasing drug resistance compared to typical chemical antiviral treatments. Since the long-term use of disinfectants and antiseptics at high concentrations has deleterious effects on well-being and the environment, this review aimed to discuss the antiviral activity of disinfectants and antiseptics needed to their activity against respiratory viruses, in particular SARS-CoV-2. . It could improve the inhibition of viral penetration into cells, the solvation of the lipid bilayer envelope and the production of ROS, thus improving the effect of disinfectants. However, concerns about the dangerous effects of nanomaterials on people and the environment are increasing as nanotechnology develops. In this review, we first discuss important and essential types of nanomaterials, especially silver and copper, that could be used as antiviral agents and their mechanisms of viral entry into host cells. Additionally, we consider the health toxicity and environmental concerns of nanoparticles. Finally, we present our vision of the future of nanomaterials in the face of viral diseases.

PMID:35266117 | DOI:10.1007/s12560-022-09517-0

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